Search results for "Pressor response"

showing 3 items of 3 documents

SYMPATHETIC NERVOUS SYSTEM AND BLOOD-PRESSURE CONTROL IN ESSENTIAL HYPERTENSION

1978

Abstract In normotensive subjects an inverse correlation was observed between an index of sympathetic nervous activity (the plasma-noradrenaline concentration during physical exercise) and reactivity to exogenous noradrenaline. This relationship was invariably disturbed in age-matched patients with essential hypertension. Multiple-regression analysis revealed a highly significant correlation between the combination of both factors and the height of mean arterial blood-pressure ( r =0·91). The findings suggest that sympathetic nervous activity and pressor response to noradrenaline together form an important determinant of the arterial blood-pressure level. An inverse relationship could be de…

AdultMaleBlood pressure controlmedicine.medical_specialtySympathetic nervous systemSympathetic Nervous SystemRestPhysical ExertionBlood PressurePhysical exerciseEssential hypertensionNorepinephrineInternal medicineReninHumansMedicineInverse correlationbusiness.industryAngiotensin IIGeneral MedicineMiddle Agedmedicine.diseaseAngiotensin IIHormonesmedicine.anatomical_structureEndocrinologyPressor responsePathophysiology of hypertensionHypertensionRegression AnalysisFemalebusinessThe Lancet
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Plasma noradrenaline and the pressor action of exogenous noradrenaline in normotensive subjects and patients with essential hypertension.

1978

1. An inverse relationship was found between plasma noradrenaline and reactivity to exogenous noradrenaline in normotensive subjects. 2. The relationship between plasma noradrenaline and reactivity was disturbed in age-matched patients with essential hypertension. 3. A multiple-regression analysis showed a highly significant correlation between adrenergic activity and reactivity to noradrenaline and the mean arterial blood pressure level (r = 0·91). The results suggest that adrenergic activity and pressor response to noradrenaline combined are important determinants of arterial blood pressure. 4. An inverse relationship could also be demonstrated between plasma renin activity and reactivity…

AdultMalemedicine.medical_specialtyPlasma noradrenalinebusiness.industryAngiotensin IIAdrenergicBlood PressureGeneral MedicineEssential hypertensionmedicine.diseasePlasma renin activityAngiotensin IINorepinephrineEndocrinologyBlood pressurePressor responseInternal medicineHypertensionReninmedicineHumansFemalebusinessClinical science and molecular medicine. Supplement
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Studies on the mechanism of mineralocorticoid-induced blood pressure increase in man.

1979

1. To gain insight into the mechanism of mineralocorticoid-induced blood pressure rise in man we performed haemodynamic studies in six normotensive volunteer subjects before and during administration of the synthetic steroid 9α-fluorocortisol (0·8 mg daily) for a period of 6 weeks. In a further study, performed in seven subjects, plasma noradrenaline concentration and reactivity to exogenous noradrenaline were determined before and during administration of the mineralocorticoid. 2. Within the first week of steroid administration an increase in mean arterial blood pressure could be demonstrated, which was due to an increase in cardiac output. After the sixth week the elevated blood pressure …

Adultmedicine.medical_specialtyCardiac outputSympathetic Nervous SystemEpinephrinemedicine.drug_classmedicine.medical_treatmentHemodynamicsBlood PressureSteroidNorepinephrineHeart RateInternal medicineReninmedicineHumansCardiac OutputVolunteerChemistryAngiotensin IIGeneral MedicineEndocrinologyBlood pressurePressor responseMineralocorticoidFludrocortisoneBlood pressure increaseClinical science (London, England : 1979)
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